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Friday, 29 May 2015

Shoddy Science - Study showing that chocolate can help with weight loss was a trick

Kashmira Gander in The Independent

A journalist seeking to lay bare how the research behind fad diets can be “meaningless” and based on “terrible science”, has revealed how he tricked international media into believing that chocolate can aid weightloss.

Posing as Johannes Bohannon, Ph.D, the research director of the fabricated Institute of Diet and Health, biologist and science journalist John Bohannon ran what he called a “fairly typical study” used in the field of diet research.

German broadcast journalists Peter Onneken and Diana Löbl asked Bohannon to conduct a clinical trial into the effects of dark chocolate, as part of a documentary exposing how simple it is for bad science to make headlines.

“It was terrible science. The results are meaningless, and the health claims that the media blasted out to millions of people around the world are utterly unfounded,” Bohannon wrote of his in an article for io9.com.

To collate their data, the team asked 5 men and 11 women aged between 19 to 67 to follow either a low-carbohydrate diet, or the same diet but with an added 1.5oz of dark chocolate. Meanwhile, a control group were asked to eat as normal.

While the data showed that the group which ate a low-carb diet while indulging in dark chocolate lost weight 10 per cent faster and had better cholesterol readings, Bohannon stressed that the study was set up for failure.

“Here’s a dirty little science secret: If you measure a large number of things about a small number of people, you are almost guaranteed to get a “statistically significant” result.”Bohannon explained that thanks to a method known as "p-hacking", the study could have just as likely shown that chocolate helped sleep or lowered blood pressure as the threshold for data being classed as "significant" is just 0.05 per cent.


The study could have just as likely shown a positive effect on blood pressure than weight loss, says Bohannon (Photo: Getty Images)THE STUDY COULD HAVE JUST AS LIKELY SHOWN A POSITIVE EFFECT ON BLOOD PRESSURE THAN WEIGHT LOSS, SAYS BOHANNON (PHOTO: GETTY IMAGES)
 

















After a journal was duped into accepting the shoddy study for money, Bohannon and his colleagues then put together a press release which would be irresistible to journalists and editors looking for a story.

The research was splashed across newspapers and websites across 20 countries in half a dozen languages, seemingly proving how easily dodgy science can circulate across the world’s media.

However, some have questioned the ethic behind the study, with one commenter writing below the piece:
"Going out of their way to court media coverage (that was going to repeat the story but never, ever follow up on the hoax once it was revealed — and this is a hoax) was ethically problematic,” one commenter said.

"If you want to uncover the shady workings, that didn’t really help. It seems like only the people who were already aware of the problems are going to be reached by this reveal."
The stunt came after Bohannon exposed how “open access”science journals were willing to publish deeply flawed research claiming that a drug had anti-cancer properties.

In the investigation for the prestigious journal Science, he revealed the dangers of abandoning the peer-review process expected in science publishing.

Tuesday, 26 May 2015

A Canadian's views on India


Tarek Fatah chats about his four-months visit to Hindustan - Bilatakalluf with Tahir Gora Ep10



Bilatakaluf with Tahir Gora TAGTV EP 07 - Is MQM victim or part of establishment?

Missing Virender Sehwag?


I think I am missing Virender Sehwag. To be fair, this is a wonderful bunch of young players and they are carrying the baton delivered to them by an extraordinary group. I find Ajinkya Rahane most pleasing to the eye, Rohit Sharma’s 264 was an audacious innings that stretched our imagination, the fielding is better than it has been and there are fast bowlers out there who don’t aspire to be medium-pacers. And I will tell people when I am old that I saw Virat Kohli bat. Cricket is still great fun but I am missing Sehwag.

Sehwag had me sitting on the edge of my seat. Always. It was like watching a thriller except that when you watched it the next time, you still didn’t know what was coming next. He was jaw-dropping, he was hair-wrenching. You rolled your eyes and you threw your head back. You looked at the scoreboard and it always showed you a different number. He could be exhilarating, he could be frustrating. He took you on a joyride and he laughed while you held on to your seat in fright.

I always thought Sehwag played cricket the way it was originally meant to be played. The numbers happened. 8586 runs in Test cricket @ 49.34 with 23 centuries. Those were brilliant numbers but we don’t need them to explain Sehwag. Or to fight his case in an argument. In cricket’s most native form, the bowler bowls to get a batsman out and the batsman plays to hit the ball. You got the feeling Sehwag didn’t worry beyond that. Only if he couldn’t hit the ball, he blocked it. You hardly ever analysed Sehwag’s innings, you just enjoyed them.

But he wasn’t a blind basher. Talking to him about cricket, and sadly those moments were too rare, you always came away thinking you had spoken to someone with an uncluttered, confident mind. “The batsman is always scared,” he once said, “but the bowler must be too. He must also think, if I bowl a bad ball where will Sehwag hit me!” The thinking behind that is clear and it has the simplicity that is disarming. If the bowler knows the batsman isn’t going to hit him, he isn’t afraid of bowling a bad ball. But he is most likely to bowl a bad ball when he is afraid of the consequences of bowling one.

We often talk, in sport, of playing to the fear in the enemy camp. Often we never get that far because of the fear in our own mind. A tense cricket match is as much about managing skill as it is about managing fear. There is scarcely a calm mind on a big day. Maybe that is why Sehwag was the most feared man in an India-Pakistan match. He played with a smile, with a song on his lips but also with a calm mind, letting fear brew within the opposition. In 9 Test matches, he made 1276 runs @91.14. It would have been interesting to have measured his pulse, especially in relation to everyone else’s!

He told us, too, that it was okay to hit in the air, to hit over the top and in doing so, he recalibrated risk for all of us. We were always told, from club cricketers to Test players, that hitting in the air was inviting another mode of dismissal. For years we accepted that as the gospel, like good boys we didn’t challenge it.

But Sehwag happily hit over the top, he played into the gap over the fielder’s head where everyone confined themselves to seeking the gap between fielders. Yes, it was still risky but with new bats, it was nowhere near as threatening as everyone believed it was.

And so he has left behind a treasure of good cheer. Which among those was his best? 201* out of only 329 against Sri Lanka when everyone else was playing on a minefield and he was on the highway? 319 against South Africa from only 304 balls while chasing 540? 309 at Multan? 254 at Lahore? That ridiculous 293 from 254 balls in Mumbai when he ended day 2 at 284 not out while still in the field at the start of play? Or was it that 83 from 68 balls with India chasing 387 to win a Test? Would anyone in the world hit eleven 4s and four 6s against a target that had only so rarely been achieved in cricket history? Sehwag often talks about facing the ball, not the bowler or the situation. Surely it had to be that way that day!

I don’t know how much I am going to see of him. I absolutely enjoyed seeing him play for the Kings XI in the IPL but what of India? Maybe the eyes aren’t seeing the ball the same way, maybe the feet are heavier, maybe the bat isn’t as charged with freedom. Maybe there isn’t the same fear in the mind of the bowler running in.

The runs are drying. You wonder if you are listening to the last bars of a lilting melody. You wonder if it is time to leave the theatre. I don’t know but if it is, it’s been an unforgettable ride.

Man who killed himself at Dignitas explains decision in film

Dan Carrier in The Guardian



Jeffrey Spector, right, at dinner with his family, said his condition could have left him with neck-down paralysis at any moment and he believed in his right to dignity. Photograph: Warren Smith 



A businessman with an inoperable tumour has killed himself at an assisted dying clinic in Switzerland – after spending his last seven days making a film for his widow and three children.

Jeffrey Spector died on Monday, six years after he was diagnosed with an inoperable tumour that was growing near his spinal column.

Doctors had warned him the condition would eventually lead to paralysis and death and so Spector said he decided he wanted to be in control of the final stages of his life.

When his illness began to get worse he decided that he had no option but to travel to Switzerland due to UK law. He said: “Assisted suicide is illegal in the UK so it had to be Switzerland.”

He added that he decided it was time when his symptoms increased in severity. “I put one date off so that my daughter could do her exams – but I was going downhill and was finding it hard to use my hands. I had no pressure in my fingers.

“I felt the illness had crossed the red line and I was getting worse. Rather than go late, I am jumping the gun. I call it the least worst option, which is best for my family in the long term.”

Spector, who was the director of a number of advertising and internet firms in Blackpool, Lancashire, chose to be joined by a film crew for the last week of his life. His decision to be filmed has echoes of the death of Guernsey-based hotelier Peter Smedley, whose assisted death in 2011 was screened in a documentary by the late Sir Terry Pratchett for the BBC.

Spector, whose family joined him at the Zurich clinic, described his condition as “a walking timebomb” as he could be struck with neck-down paralysis at any moment.

In an interview released by Dignitas, Spector said he was not scared of death and added: “Never judge someone until you have worn their shoes.

“I know I am going too early. My family disagree, but I believe this is in their best interests.” Stating he wanted to be “in control of the final stages of my life”, he said: “I was a fit and healthy person and my life has been turned upside down.

“What started as backache in 2008 developed into an illness that led me to having to make this most awful decision. Friends, and most of all my family, have urged me not to go through with it.”

Spector first discovered he was ill when he complained of having a sore back and stiff neck. He collapsed at a hotel after attending a friend’s retirement party and sought medical advice. He said: “I thought I had overdone things. My legs went in the hotel room. I got back home and booked in for an MRI scan.

“The phone call from the clinic asked me to go for another scan, which revealed a large tumour high up in my spine in and around the spinal cord.

“My surgeon was confident he could remove the tumour but tests revealed it would be too dangerous. I woke up thinking it would be out, but he told me he could not even take a biopsy.”

Instead, surgeons removed bones elsewhere in his back to relieve pressure caused by the tumour, but it continued to grow.

Spector added: “Had it been lower down the spine, and I lost the use of my legs, I would have been distraught but I could cope. Where it was meant total paralysis from my neck down.”

As the tumour grew, Spector visited the Dignitas clinic and decided that he would kill himself before the tumour’s advance meant he would be unable to do so.

He said: “I know I am going too early but I had consistent thoughts without peer pressure. It had to be a settled decision by a sound mind. If I am paralysed and cannot speak, then what hope is there? I am a proud person – a dignified person, independent and self motivated. It is me who is doing this.”

In the UK, anyone convicted of assisting a suicide can face a 14-year jail term. Pressure group Dignity In Dying, which counted Pratchett as one of its patrons, have long campaigned to change the law.

Labour peer Lord Falconer proposed a bill stating that if someone has a prognosis of less than six months to live, they should be allowed to have an assisted death subject to a number of safeguards and checks. His private member’s bill was debated in the House of Lords in June 2014 and reached the committee stage in parliament in January. However, due to opponents delaying its progress, the bill did not reach the Commons before parliament was dissolved ahead of the general election.

“Some people will criticise me, but do not judge me,” said Spector. “I believe in my human right to dignity. I want the ability to have a cup of tea and hold a phone – I want to be able to do those things myself.

“I believe what I am doing is in the best long term interests of my family. They disagree, but they do accept I have my own opinion.”

A family friend said on Monday: “Jeffrey was not for changing his mind. He did not want to be unable to walk or talk.

“From the outside he appeared as normal – chatty, driving his car, but inside he knew he was getting worse. People have tried to talk him out of this, his own family have begged him.

“But if Jeffrey Spector could not be the Jeffrey Spector we all knew, because of this tumour, this was his way out.”